Irene,

You didn't say how long you are thinking of using colloidal silver (CS), but if it is going to be ongoing, you might want to reconsider :

https://pubmed.ncbi.nlm.nih.gov/28617070/#:~:text=Our study shows how long, necrotic cell death in kidneys.

Here is a relevant quote :

' Our study shows how long term AgNPs exposure may promote ultrastructural damage to kidney causing inflammation and expression of cell survival factors. These changes, in the long term, could lead to inhibition of the beneficial apoptotic pathway and promotion of necrotic cell death in kidneys. '

On a related note, Grape Seed Proanthocyanidin Extract (GSPE) has shown the ability to improve renal failure in CKD patients as well as lower Uric Acid levels :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083963/

Here is a relevant quote from the study :

' First of all GSE improves some kidney function parameters as it enhances GFR and clearly lowers proteinuria. This result is of utmost importance as reduction in proteinuria to the lowest achievable level is an important predictor of long term renal protection (de Zeeuw et al., 2004[13]), as it is increasingly recognized that proteinuria may actually be pathological and etiological in CKD progress and not just symptomatic (Roscioni et al., 2014[38]). An association between hyperuricemia and CKD in middle-aged population has also been recently described (Zhu et al., 2014[48]). As in our present case GSE affects both plasma, urine urea and uric acid, its clinical use could be envisaged as an uric acid-lowering therapy substitute to allopurinol. '

Lastly, GSPE may help with the leukocyte level and related inflammation, at least in rats :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776444/

Here are two relevant quotes :

' A marked reduction on the inflammatory mediators, edema volume and oxidative byproducts in edema bearing rats' prophylactic and treated with grape seeds extract and indomethacin was observed. Indomethacin found to induce some toxicological impacts which minimized when administered together with GSE. '

' GSE is a safe antioxidant agent with anti-inflammatory property. '

Art

Irene, Regarding Colloidal Silver (CS), I would like to further clarify, although I don't think CS would normally be a problem for kidneys, in the case of kidneys that are already compromised due to an existing Chronic Kidney Disease diagnosis, I do think CS may expose you to unneeded risk of further kidney damage if enough is consumed based on the study I linked to. That is the reason I suggested considering GSPE as a safer consideration under the specific condition that you are dealing with. Art

Thank you Art,

Your input is so appreciated. I would never take CS long term. Only 3 or 4 days. The little indicator on the urine test is a shade less purple. Whether it is the baking soda or CS or both, I'm not sure.

I did find this on your site.

https://www.earthclinic.com/mobile/supplements/colloidal_silver/kidney-infection/

The diet info is so discombobulating. Eat cabbage, don't eat cabbage, eat citrus, don't eat citrus.

My daughter was once diagnosed with stage 4 kidney disease. They were talking transplant. It was very distressing for her. She was in her 30s, with 3 young children. She decided to get a second opinion. It seems the first diagnosis was wrong. Her kidneys were fine. Now, she is very healthy and in late 40s. Unfortunately, I have a huge distrust of pharmaceutical companies. I will look up the Grape Seed.

Thank you again.

Irene

You're welcome, Irene! Btw, Deirdre is the owner of EC, I am just a regular poster on EC.

Yes, Colloidal Silver (CS) is an amazing product and can destroy a multitude of pathogens and also be synergistic with certain antibiotics and certain cancer treatments, but it also can kill good gut bacteria and human cells and with kidney disease, there could be potential, however slight, for further damage and that is why I leaned toward the GSPE because it has potential to do much of what you want with significantly less potential for increased kidney damage compared to CS. If you had a kidney infection, as in the post you linked to as opposed to chronic kidney disease (CKD), I could definitely see using CS and I have seen that option used for kidney infection to good effect. With CKD, the situation is different than kidney infection and I tend to err on the side of caution.

The following review suggests that the gut microbiome can have an impact on kidney disease when there is dysbiosis present :

https://www.frontiersin.org/articles/10.3389/fmed.2021.790783/full#:~:text=Microbial Dysbiosis in CKD, -The dominant bacterial&text=The interplay between bacteria present, outcomes (24, 61).

Here is a relevant quote from the review :

' The interplay between bacteria present in the gut (and their metabolites) and kidney function is occasionally referred to as the gut–kidney axis (90). Recent studies indicate that aberrant gut microbiota has a key role in the pathophysiology of CKD with severe CKD outcomes (24, 61). '

GSPE is generally well tolerated by many people and has shown to have a positive impact on the gut microbiome as discussed here :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054226/#:~:text=(11), grape seed extract, gut function and IBD symptoms.

Here is a relevant quote :

' In the study of Wang et al. (11), grape seed extract rich in polyphenols increase the abundance of non-pathogenic bacteria in the gut, contributing to the improvement of gut function and IBD symptoms. Also, these dietary bioactive compounds impact the colon positively by affecting the transit time and the production of SCFAs that further affect the pH and enhance the gut barrier properties along with also a protective effect on the colonic mucosa (13). '

CKD is sometimes caused by high blood pressure or diabetes or both. If you had diabetes, I likely would have suggested something else before or with GSPE, but you did not mention diabetes and so I suggested the GSPE. If you have high blood pressure (HBP), I would have suggested an additional supplement to be used along side the GSPE, but you didn't mention HBP, so I didn't. There are other causes of CKD, but you didn't mention if the cause is known or not.

In any case, good luck and keep us posted on your progress!

Art